Pulmonary Hypertension – Diagnostic and Therapeutic Options

نویسندگان

  • Marko Jakopović
  • Ana Hećimović
  • Mateja Janković
  • Miroslav Samaržija
چکیده

Pulmonary hypertension is a complex group of diseases characterized by a common denominator: elevated pressure in the pulmonary circulation. The etiology of pulmonary hypertension can be very various. The first step in successful treatment of pulmonary hypertension is early detection of this serious and potentially fatal disease. Very important is the suspect about the disease and send patient to additional diagnostic procedures. The most effective diagnostic method for screening today is echocardiogram, which can indirectly measure pressures in the pulmonary circulation and evaluate function of the right ventricle. The final diagnostic method proving pulmonary hypertension is right heart catheterization. In the treatment of pulmonary hypertension different medications are used: calcium channel antagonists, prostaglandins, endothelin antagonists and inhibitors of phosphodieserase. In patients whom medical therapy is not effective lung transplantation remains a final step.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Thalassemia Associated Pulmonary Hypertension

Cardiac disease is the main cause of death in both forms of thalassemia; thalassemia major (TM) and thalassemia intermedia (TI). Pulmonary hypertension (PH) is one of the cardiopulmonary morbidities with high mortality that, if not treated, may trigger right-sided heart failure and premature death. PH is defined as a mean pulmonary artery pressure of ≥25 mmHg at rest or ≥30 mmHg during exercise...

متن کامل

Recent Trends in the Management of Pulmonary Hypertension

Context. Pulmonary hypertension is a common clinical problem encountered in day-to-day practice. Drug therapy forms the backbone of management and appropriate drug selection is based upon the underlying causes. The options available are widening with availability of newer therapeutic agents and thus it becomes necessary to be updated with the recent developments. Objective. To review the existi...

متن کامل

The Adult Patient with Eisenmenger Syndrome: A Medical Update After Dana Point Part I: Epidemiology, Clinical Aspects and Diagnostic Options

Eisenmenger syndrome is the most severe form of pulmonary arterial hypertension and arises on the basis of congenital heart disease with a systemic-to-pulmonary shunt. Due to the chronic slow progressive hypoxemia with central cyanosis, adult patients with the Eisenmenger syndrome suffer from a complex and multisystemic disorder including coagulation disorders (bleeding complications and parado...

متن کامل

Pulmonary vascular complications in portal hypertension and liver disease: a concise review.

Chronic liver disease and/or portal hypertension may be associated with one of the two pulmonary vascular complications: portopulmonary hypertension and hepatopulmonary syndrome. These pulmonary vascular disorders are notoriously underdiagnosed; however, they have a substantial negative impact on survival and require special attention in order to understand their diagnostic approach and to sele...

متن کامل

Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice

Pulmonary hypertension (PH) is an often-fatal vascular disease of unclear molecular origins. The pulmonary vascular remodelling which occurs in PH is characterised by elevated vasomotor tone and a pro-proliferative state, ultimately leading to right ventricular dysfunction and heart failure. Guided in many respects by prior evidence from cancer biology, recent investigations have identified met...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015